The Patagonia & Mythical Route 40 itinerary takes you on an unforgettable journey through Patagonia’s stunning landscapes from north to south. Explore Bariloche and the picturesque Lake District, where turquoise lakes, lush forests, and majestic mountains create breathtaking scenery. Visit Los Antiguos and the Marble Cathedrals, then discover the iconic Cueva de las Manos, featuring rock paintings over 9,000 years old. Continue south to El Chaltén for world-class trekking among mountains and forests, and El Calafate for incredible glacier tours. Finally, reach the End of the World in Ushuaia and sail the Beagle Channel. All trips are fully customizable to match your interests, preferred activities, travel dates, and destinations.
Boat trip on Lake Nahuel Huapi and the Arrayanes Forest.
Adventure day in Bariloche with kayaking or mountain biking.
Visit to Los Alerces National Park near Esquel.
Crossing into Chile to see the stunning Marble Cathedrals.
Exploration of the ancient Cueva de las Manos archaeological site.
Trekking to Laguna de los Tres and Mount Fitz Roy in El Chaltén.
Visit to the world-famous Perito Moreno Glacier.
Gourmet navigation among glaciers on Lake Argentino.
Trekking and canoeing in Tierra del Fuego National Park.
Navigation along the Beagle Channel and penguin encounter on Martillo Island.


On the third day of the Patagonia & Mythical Route 40 itinerary, choose between an active adventure or a quieter day.
Kayaking in Lago Mascardi: Paddle along the Tronador Arm of Lake Mascardi in Nahuel Huapi National Park, surrounded by turquoise waters, lush forests, and views of Tronador and Bonete Hills. Stop at a remote beach for lunch and relaxation. Basic kayaking instructions are provided.
Cerro Catedral Mountain Biking: Explore the Bike Park at Cerro Catedral with guided routes suitable for all levels. Enjoy thrilling descents, panoramic views of Lake Gutiérrez and Lake Moreno, and the surrounding mountains. Transfers from your hotel to the resort are included.


Travel south from Esquel to Los Antiguos in about seven hours. Spend the afternoon exploring the town at your leisure, enjoying local cuisine, and taking in the beautiful lakeside and mountain scenery.

The scenic winding road leads to the Austral Route, and after two hours, you reach Puerto Río Tranquilo. From here, take a boat to explore the Marble Cathedrals, stunning calcium carbonate formations sculpted by the lake’s waters into cave-like structures resembling religious architecture. Boats allow close-up views and entry into several caverns, offering a unique, immersive experience in this Chilean natural sanctuary.

Cueva de las Manos, perched 88 meters above the Pinturas River, is one of Patagonia’s most important archaeological sites. Explore its caves with a guide, admiring over 9,000 years of cave paintings, including hands, animals, and symbols, along a 2 km round-trip route.
After the visit, resume your journey to El Chaltén, arriving around 9:00 p.m., ready for the next stage of your Patagonian adventure.








Say goodbye to the wonderful Patagonia. Your local driver will take you to the Ushuaia airport to catch your flight to the next destination.
Transportation throughout the trip
Accommodation
Expert local guides
Full support from your Travel Agent before, during, and after the trip
International or domestic flights
National Park Tickets
Personal expenses and optional activities
To start this journey, travelers will need to fly into El Calafate Airport Aeropuerto Internacional Comandante Tola (FTE), located just outside El Calafate City. This airport receives domestic flights from Buenos Aires (Aeroparque Jorge Newbery – AEP) and international connections via Buenos Aires Ezeiza (EZE).
Arrival Flight: Traveler flies from origin city to Buenos Aires Ezeiza (EZE) or Aeroparque (AEP), then connects with a domestic flight to El Calafate Airport (FTE).
Departure Flight: At the end of the itinerary, travelers will take a domestic flight from Ushuaia Airport (USH) back to Buenos Aires (EZE/AEP) for onward international connections.
Plan your perfect Argentina adventure with personalized guidance
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Contact a destination specialist, who will take the time to fully understand your preferences and ideas and turn them into the perfect itinerary for you according to your budget. The itinerary can be modified as many times as you want until you are completely happy with the result.
All Southwind Experience journeys are 100% tailor-made.
Add an extra night in El Chaltén to enjoy additional trekking routes such as Loma del Pliegue Tumbado or Laguna Torre.
Extend your stay in El Calafate with a night at a traditional Patagonian Estancia, including horseback riding and a classic lamb barbecue.
Include a few days in Torres del Paine National Park (Chile) for one of the world’s most breathtaking trekking experiences.
Add leisure or spa days at any point in the trip to relax and recharge after several days of adventure.
Your dedicated travel specialist will help you adapt the itinerary according to your interests, travel style, and preferred dates — ensuring your Patagonia journey is exactly as you imagine it.
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